Paul Scholes believes Manchester United manager Erik ten Hag could be forced into a change of system following the loss of Raphael Varane to injury.
The centre-back was forced off on the hour mark during Saturday's 1-1 draw with Chelsea at Stamford Bridge and was visibly distressed as he left the pitch.
The former Real Madrid man has been central to United's improvement under Ten Hag in recent weeks, and with Harry Maguire also sidelined, United now find themselves short of options in the midst of a busy period in the season.