Jack Willis makes an emotional return to England’s starting line-up on Sunday - with Owen Farrell set to be named at fly-half.
Head coach Steve Borthwick has rung the changes for the visit of Italy - the very fixture in which Willis suffered a career-threatening knee injury two years ago.
Farrell is expected to revert to fly-half for the first time since Marcus Smith burst onto the international scene in July 2021, with specialist centres Henry Slade and Ollie Lawrence combining in midfield.