
A trio of researchers has won the 2025 Nobel Prize in Physiology or Medicine for discovering how the immune system is prevented from attacking our own bodies.
Mary E. Brunkow of the Institute for Systems Biology in Seattle, Fred Ramsdell of Sonoma Biotherapeutics in San Francisco, and Shimon Sakaguchi of Osaka University in Japan were awarded the prize "for their discoveries concerning peripheral immune tolerance." The Nobel Assembly at Karolinska Institutet announced the winners at a ceremony in Stockholm, Sweden, on Monday (Oct. 6).