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The Guardian - UK
The Guardian - UK
Science
Nicola Davis Science correspondent

Nobel prize in medicine awarded to scientists for immune system research

A screen showing the photos of Mary E Brunkow, Fred Ramsdell and Shimon Sakaguchi
Mary E Brunkow, Fred Ramsdell and Shimon Sakaguchi will share the 11m-kronor prize (about £871,400). Photograph: Claudio Bresciani/AP

The Nobel prize in physiology or medicine 2025 has been awarded to three scientists for their work on how the immune system is prevented from attacking the body.

Mary E Brunkow, now at the Institute for Systems Biology in Seattle, Fred Ramsdell, now at Sonoma Biotherapeutics in San Francisco, and Shimon Sakaguchi, now at Osaka University in Japan, have been awarded the prize “for their discoveries concerning peripheral immune tolerance”.

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