Billions of people around the world have received the Pfizer or Moderna COVID-19 vaccines. The rapid development of these vaccines changed the course of the pandemic, providing protection against the SARS-CoV-2 virus.
But these vaccines would not have been possible it if weren’t for the pioneering work of this year’s winners of the Nobel prize in physiology or medicine decades earlier.
Dr Katalin Karikó and Dr Drew Weissman, researchers from the University of Pennsylvania, have been given the prestigious award for their discoveries into mRNA biology. The pair were the first to discover a way of modifying mRNA that allowed it to successfully be delivered to cells and replicated by them.