Week 18 of the 2025 NFL season closes the regular season on January 3-4 with division titles, wild-card spots, and playoff seeding still live across both conferences – and the official injury report is a brutal one. The Commanders enter Philadelphia with both QBs Jayden Daniels and Marcus Mariota ruled OUT, leaving Washington scrambling at the most important position in football in the most consequential game of their season. The Lions, Eagles, Vikings, and Jets each carry five or more OUT designations into high-stakes matchups. On the other end of the spectrum, the Pittsburgh Steelers are the only team in the entire 32-team league with no players listed on the injury report heading into an AFC North showdown at Acrisure Stadium. Two quarterbacks OUT, one DOUBTFUL in the Chiefs game, and a Saints backfield without Alvin Kamara round out the most disruptive cross-slate injury picture of the regular season.
Here is the full breakdown, game by game, drawn from the official NFL.com injury report for all 16 Week 18 matchups. You can also track how these rosters shifted over the final month of the season in the Week 17 injury roundup.
