
For the first time, scientists have tested a messenger RNA (mRNA) vaccine in a patient with a deadly form of brain cancer — and it triggered a strong immune response.
The vaccine, which was described in a study published on May 1 in the journal Cell, was created by extracting genetic material called RNA from a tumor from a patient with glioblastoma, an aggressive type of cancer. The RNA was then replicated to make a vaccine from mRNA, which is a blueprint for what is inside every cell, including tumor cells.