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LiveScience
LiveScience
Jennifer Zieba

New mRNA vaccine for deadly brain cancer triggers a strong immune response

Glioblastoma brain cancer. Coloured computed tomography (CT) scan of a section through the brain (side-view) of an 84-year-old female patient with glioblastoma (dark, top). .

For the first time, scientists have tested a messenger RNA (mRNA) vaccine in a patient with a deadly form of brain cancer — and it triggered a strong immune response.

The vaccine, which was described in a study published on May 1 in the journal Cell, was created by extracting genetic material called RNA from a tumor from a patient with glioblastoma, an aggressive type of cancer. The RNA was then replicated to make a vaccine from mRNA, which is a blueprint for what is inside every cell, including tumor cells.  

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