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The Guardian - UK
The Guardian - UK
Science
Anna Bawden Health and social affairs correspondent

New GLP-1 pill helps patients lose up to 8% of body weight, trial shows

Close-Up of a Hand Holding Pills and a Blister Pack
Orforglipron is not has not yet been approved by regulators in the UK, US or Europe. Photograph: Ekaterina Goncharova/Getty Images

A new daily pill could be a more effective GLP-1 tablet for weight loss, according to a clinical trial that may pave the way for an improved non-injection alternative to Wegovy and Mounjaro.

The drug, called orforglipron and manufactured by Eli Lilly, is prescribed for type 2 diabetes and targets the same GLP-1 receptors as oral semaglutide. Like semaglutide, it lowers blood sugar levels, slows digestion and suppresses appetite. Unlike semaglutide tablets, it does not need to be taken on an empty stomach.

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