Lupe Samano had been bed bound for 12 years as a result of her food addiction, but she now looks completely different after losing more than half her body weight.
The My 600lb Life star weighed in at 642lb (45.8 stone) when she appeared on the TLC reality show and was desperate to turn her life around after slipping into a diabetic coma early in her life.
Lupe's weight soared to 35.7 stone (500lb) by the time she was a teenager and she said she had reached the point of severe depression.