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Kory London, Associate Professor of Emergency Medicine, Thomas Jefferson University

Medetomidine is replacing xylazine in Philly street fentanyl − creating new hurdles for health care providers and drug users

Medetomidine is now a key ingredient in street fentanyl sold in Philly. AP Photo/Matt Rourke

Philadelphia’s street opioid supply – or “dope” market – is constantly changing. As health care workers and researchers who care for people who use drugs in our community, we have witnessed these shifts firsthand.

New adulterants are frequently added to the mix. They bring additional and often uncertain risks for people who use drugs, and new challenges for the health care providers and systems who treat them.

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