DEAR MAYO CLINIC: My friend insists that taking a probiotic supplement has helped her lose 50 pounds by keeping her gut bacteria in check. Will taking a probiotic in conjunction with a balanced diet and exercise help me lose weight?
ANSWER: It is true that the gut bacterial population in people who are obese differs from the population in people who are lean. Whether this difference contributes to obesity or is a consequence of obesity is unknown.
So far, research hasn't yielded clear answers. Although taking a probiotic is unlikely to cause harm, it may not help fight obesity.