Manchester United will assess Raphael Varane over the next 24 hours to determine the severity of his injury.
Varane came off in the 60th minute against Chelsea in what was his second injury of the month, having limped off against Manchester City three weeks ago. The 29-year-old appeared to conceal tears before he walked around the pitch to the dugout unaided.
"Nothing in this moment," United manager Erik ten Hag replied when asked about Varane. "We have all seen he came off but with an injury like this we always have to wait a minimum 24 hours and the medical staff can do their job and can set the diagnosis.