West Ham travel to Old Trafford where they look to pick up their first away win in the Premier League against Manchester United for the first time in 15 years.
The Irons are 29/10 with Grosvenor Sport while Man United are favourites at 10/11 and a draw is 11/4.
David Moyes' side look to increase their gap in the top four with Tottenham only one point behind them with three games-in-hand and Arsenal two points behind with two games-in-hand.