A man is seriously injured and three teenagers have been arrested following a stabbing in Melbourne's CBD.
There was an altercation at about 3.20am on Saturday at Flinders Street involving a number of people, police say.
A 21-year-old man was stabbed, suffering serious injuries to his stomach and hands.
Shortly afterwards three teenagers were arrested at Southbank near the Arts Centre.
A 17-year-old from Footscray and two 16-year-olds from Tullamarine and Spotswood are assisting police with inquiries.
Anyone who witnessed the incident or with information about what happened are urged to come forward.