
Drew Brees and Peyton Manning helped define a generation of quarterbacks in the 21st century.
While they rarely met on the field, recording only four matchups during their 15 years in the NFL together, they set the standard for accurate and prolific quarterbacks who had total command of their offense. Brees emerged victorious in the most significant battle between the two—Super Bowl XLIV, in which Brees's New Orleans Saints beat Manning's Indianapolis Colts, 31-17. Manning retired following the 2015 season, but Brees had one last win over Manning in him before he hung up his own cleats.