Joe Gomez was withdrawn at half-time of Liverpool's trip to Southampton with a suspected ankle injury.
The defender was hurt when Mohammed Salisu landed awkwardly on him in first-half stoppage-time at St Mary's with the scores level at 1-1.
Gomez was taken to the sidelines but Liverpool boss Jurgen Klopp refused to make the change initially, preferring to give his player the benefit of some treatment during the interval to see how he responded.