Jurgen Klopp makes six changes as Liverpool are hosted by Rangers in the Champions League - with Mohamed Salah and Thiago Alcantara on the bench.
Harvey Elliott and Fabio Carvalho start for the Reds as they aim to take a significant step toward qualification for the knockout stages in their first ever competitive trip to Ibrox.
Ibrahima Konate and Joe Gomez step in for injured defenders Trent Alexander-Arnold and Joel Matip as Fabinho returns to midfield alongside captain Jordan Henderson and in place on Thiago.
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Liverpool's back-four of Gomez, Konate, Van Dijk and Tsimikas has only previously been named once before this evening - in a 1-0 win over Nottingham Forest in the FA Cup in March.
Roberto Firmino also starts for Klopp in Glasgow alongside Darwin Nunez as Diogo Jota is reserved for the bench along with Salah.
Nunez is named up top as he aims to build on his performance and goal in the 3-2 Premier League defeat at Arsenal on Sunday afternoon, which also saw Luis Diaz go off injured.
Liverpool : Alisson; Gomez, Konate, Van Dijk, Tsimikas; Fabinho, Henderson; Elliott, Firmino, Cavalho; Nunez. Subs: Adrian, Kelleher, Thiago, Milner, Salah, Jota, Robertson, Phillips, Bajcetic.
Rangers: McGregor, Tavernier, Goldson, Davies, Barisic, Lundstram, Jack, Arfield, Sakala, Kent, Colak. Subs: McLaughlin, McCrorie, Yilmaz, Davis, Matondo, Sands, Morelos, Wright, Tillman, Devine, King.
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