Kaide Gordon, Conor Bradley and Owen Beck could all be involved against Norwich City on Wednesday night after being left out of the Liverpool Under-19s side to face Genk.
Tyler Morton was also missing from the side but remains an injury doubt after being pictured on crutches, having come off injured in the Under-23s' win over Arsenal on Friday night.
The young Reds host the Belgian outfit at the Academy in their one-legged last-16 knockout tie in the UEFA Youth League at 2pm on Wednesday.
The quartet, along with winger Harvey Blair, have all featured for Jurgen Klopp ’s first team and in the UEFA Youth League so far this season.
But as the Under-19s prepared to face Genk, all five were missing from the matchday squad to take on the Belgians.
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And with the German expected to rotate his side against Norwich in the FA Cup following Sunday’s League Cup final victory over Chelsea, the absence of Gordon, Bradley and Beck from Marc Bridge-Wilkinson's squad could suggest they have been reserved for FA Cup action instead.
However, it is also worth noting that Gordon, Beck and Blair were all spotted at the AXA Training Centre cheering on their team-mates in the first half of their UEFA Youth League clash with Genk. As a result, it might only be Bradley who has been given a senior call-up.
While the quintet didn't face Genk, Billy Koumetio, Max Woltman, James Norris and Melkamu Frauendorf, who have also all played for Klopp’s first team this season, were all named in Liverpool Under-19s' starting XI to face the Belgians.
Liverpool U19s starting XI vs Genk: Davies; Mabaya, Koumetio, Quansah, Norris; Corness, Balagizi; Frauendorf, Musialowski, Woltman; Cannonier.
Subs: Mrozek, O'Rourke, Clark, Jonas, Miles, Scanlon, Pilling.