PITTSBURGH — Bill Ludwig and Doug Olson's own immune cells cured them from cancer.
In 2010, the two men were battling a type of blood cancer called chronic lymphocytic leukemia that was once deemed incurable.
Both had undergone several rounds of traditional treatments, but their cancer kept coming back. Out of options, they volunteered for a clinical trial of an experimental therapy at the University of Pennsylvania that would modify their own cells to target and selectively kill cancer cells. The approach is known as CAR-T cell therapy.