Following the jubilation of the dramatic midweek victory against Marseille, which saw Spurs qualify top of their Champions League group, misery has engulfed Spurs' return to Premier League action after they slumped to a 2-1 defeat against Liverpool at Tottenham Hotspur Stadium.
Two first half strikes from Mohamed Salah put Liverpool in control and while Antonio Conte's side rallied back in the second half, as they have done many times this season, Harry Kane's goal 20 minutes from time was merely a consolation.
For the third consecutive Premier League game, Spurs went two goals behind before they actually began competing on the pitch, except this time, unlike last weekend's heroics against Bournemouth, the damage was too severe and Liverpool were able to leave north London with their first away league win of the season.