
Bone Biologics Corporation (BBLG) in Burlington, Mass., is a medical device company that focuses on bone regeneration in spinal fusion using recombinant human protein. The company’s NELL-1/DBX is a combination product. It is an osteostimulative recombinant protein that provides target-specific control over bone regeneration. BBLG’s platform technology has applications in delivering enhanced outcomes in the surgical specialties of spinal, orthopedic, general orthopedic, plastic reconstruction, neurosurgery, interventional radiology, and sports medicine.
On March 7, 2022, BBLG announced a supply agreement with MTF Biologics for demineralized bone matrix (DBM). BBLG CEO Jeff Frelick, said: “This DBM supply agreement is an important milestone that allows us to advance rhNELL-1 for the $3 billion spine fusion market, with the goal of developing a product with compelling features and benefits versus existing commercial products.”