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The Economic Times
The Economic Times
National
Piyush Shukla

In 2017, two parents asked scientist Stanley Crooke to create treatments for their children's rare mutations. Years later, a custom drug cut one boy's seizures by 90% and helped him walk on his own for the first time

For most of his childhood, Connor Dalby could not walk without help. His life was shaped by seizures, developmental problems and constant medical care. Then an experimental custom drug changed what his family thought was possible. The treatment was designed around Connor's specific genetic mutation. It did not simply treat symptoms. It targeted the faulty copy of a gene involved in his epilepsy. Within months, his seizures had fallen by 90%. He also began taking steps without assistance for the first time. His story is now raising a bigger question about medicine: what if some drugs could be designed for one patient at a time?

How a custom drug began with two parents and an unusual idea

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