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Synphane Gibbs-Shelton, Ph.D. Candidate in Pharmacology, University of Virginia

Immune cells in the brain may reduce damage during seizures and promote recovery, according to study in mice

Microglia perform many functions in the brain, and their role in seizures is unclear. KTSDesign/Science Photo Library via Getty Images

Seizures are like sudden electrical storms in the brain. Seizure disorders like epilepsy affect over 65 million people worldwide and can have profound effects on a person’s quality of life, cognitive function and overall well-being. Prolonged seizures called status epilepticus can cause lasting brain damage.

Specialized immune cells in the brain called microglia are activated during seizures to help clean up the damage. Researchers don’t fully understand exactly how these cells are involved in seizures. Some studies have found that microglia promote seizures, while other studies show the opposite.

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