Cancer is one of the most fatal health problems globally. A recent Indian Council of Medical Research (ICMR) report indicated that the number of people living with this deadly disease continues to rise. The National Cancer Registry Program reported that one in nine people in India are likely to develop cancer in their lifetime and 14,61,427 people are currently living with cancer. There is a 12.8% increase in cancer incidence every year since 2022.
Despite having a high cancer incidence, India has been under-represented in global cancer genome studies. In the absence of genomic architecture of cancers prevalent in India, specific genetic variants from Indian cancers are not adequately captured and catalogued for any diagnostic kits and drug development.