Leeds United duo Brenden Aaronson and Tyler Adams will be opening their World Cup campaign against Wales on Monday night as both sides look to get a good start to their group.
The USMNT didn't qualify for the last World Cup so many of their young players that have come through the ranks are an unknown quality on the international stage.
Wales, on the other hand, are participating in their first World Cup since 1958 where they made the quarter-finals before being knocked out by a Pele goal in a 1-0 loss to Brazil.