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ABC News
ABC News
Health
science reporter Belinda Smith for Catalyst

How changes in oestrogen levels before, during menopause can affect how we think and feel

Menopause Brain Oprah Winfrey
Sex hormones such as oestrogen act directly on brain cells, and can alter mood and cognition. (Getty Images: Ponomariova_Maria)

The year 2003 marked more than one turning point in Oprah Winfrey's life: she became the first Black American woman billionaire, and she reached menopause.

In a recent chat with gal pals Maria Shriver and Drew Barrymore, the queen of daytime talk shows said when she started "The Big M" at age 48, she couldn't focus.

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