New research in the general population, followed for far longer than any previous work on this sweetener, found that people with the highest blood levels of xylitol had a 57 percent higher risk of major adverse cardiovascular events over six years than those with the lowest levels.
That figure comes from the Canadian Longitudinal Study on Aging. In a second cohort followed for 30 years, the European Prospective Investigation into Cancer study in Norfolk, England, the increase was 18 percent. Together the two datasets covered 17,710 participants.