Genetic variant identified that may increase multiple sclerosis severity

People who inherit the genetic variant from both parents need a walking aid almost four years sooner than those without, the study found. Photograph: Sandra Baker/Alamy

Researchers have discovered a genetic variant that appears to influence the speed at which multiple sclerosis (MS) progresses, potentially paving the way for new treatments.

According to the MS International Federation, about 2.9 million people worldwide have MS, a condition in which the insulating coating of the nerves in the brain and spinal cord is damaged by the immune system. The nerve fibres themselves can also become damaged.