Gary Neville's Relentless Group has partnered with the property developer owned by Betfred founder Fred Done to build a 40-storey tower at its St Michael's scheme in Manchester city centre.
Salboy will lead the project, which forms the second phase of the scheme, after signing a joint venture agreement.
The tower will include a five-star hotel with 161 beds, 181 serviced residences and a "multitude of design-led amenity and leisure spaces".