Frank Lampard has named an unchanged side at Southampton after victory over Leeds United last weekend.
Alex Iwobi and Jonjoe Kenny both keep their places as Vitalii Mykolenko returns to the bench following injury.
Jordan Pickford is in goal for Everton while his defence is made up of captain Seamus Coleman, Mason Holgate, Michael Keane and Kenny, who excelled in an unfamiliar left-back position against Leeds.
Donny van de Beek retains his midfield role alongside Allan as Richarlison, Anthony Gordon and Iwobi support Dominic Calvert-Lewin.
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Mykolenko returns to the bench alongside Dele Alli, Nathan Patterson, Andros Townsend, Asmir Begovic, Andre Gomes, Jarrad Branthwaite, Salomon Rondon and Anwar El Ghazi.
Jean-Philippe Gbamin misses out of the matchday squad entirely and is subject to interest from CSKA Moscow.
The ECHO understands the Russian side are looking to take the 26-year-old on loan for the remainder of the campaign.
Everton: Pickford; Coleman, Holgate, Keane, Kenny; Van de Beek, Allan; Iwobi, Richarlison, Gordon; Calvert-Lewin
Substitutes: Dele, Patterson, Townsend, Begovic, Mykolenko, Gomes, Branthwaite, Rondon, Ghazi
Southampton: Forster, Livramento, Salisu, Bednarek, Walker-Peters, Elyounoussi, Romeu, Ward-Prowse, Armstrong, Adams, Broja
