GWS veteran Phil Davis is on track to feature in the club's AFL season opener against Adelaide on Sunday, while fit-again duo Brent Daniels and Jack Buckley are a chance to join him.
Davis played just five games last season after tearing his left hamstring in March and his right hamstring in July.
The 32-year-old made it through a VFL practice match last week to put his hand up to take on the Crows at Giants Stadium.
"Phil is certainly in contention for round one," new GWS coach Adam Kingsley told reporters on Monday.
"He spent a lot of the pre-season recovering from hamstring surgery, so he's had a delayed start to the (summer).
"But he's back fully training. He played in the VFL last week and our intraclub down in Canberra the week before.
"He's been playing key back, that's where he's been a great player for this footy club for a long time.
"He's in contention, we'll see how the training week goes. But certainly pleased with his progression returning from injury, and there's every chance he'll play."
There could be two other feel-good stories.
Daniels missed all of last season due to a string of hamstring injuries, and he suffered a fresh setback in February.
But the small forward is firming for a spot against the Crows after making strong recent progress.
And promising young defender Buckley, who hasn't featured at AFL level since tearing the ACL in his left knee in round 16, 2021, is also pushing hard for a berth after a strong outing in the VFL practice match.
"He's on the cusp of the team at the moment," Kingsley said of Buckley.
"He got through a practice match at VFL level last week, played three-and-a-half quarters.
"He looked really good. Strong, competitive, quick are all his attributes. He'll be in discussions."
Recruit Toby Bedford is set to miss the first two months of the season after tearing his hamstring in February.
Kingsley has been impressed by the leadership qualities shown by Toby Greene, who was appointed the club's sole skipper during the off-season.
"The way he plays typifies what a captain and how a captain should play. He doesn't need to do anything different," Kingsley said.
"Across the course of the last two or three months, I've seen a guy who is an incredibly hard worker on and off the field.
"He leads his teammates not necessarily with great speeches or words, but through actions."
The Giants lost Tim Taranto, Jacob Hopper, Tanner Bruhn and Bobby Hill during the off-season, leaving Kingsley with an uphill battle to guide the side to finals action in his first year.