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Alistair Mathie, Professor of Pharmacology and Head of Life Sciences, University of Westminster

First new non-opioid painkiller approved in the US for decades – here’s how it works

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A new non-opioid painkiller, suzetrigine, has just been approved by the US drug regulator, the FDA. It is the first non-opioid painkiller the agency has approved in over two decades.

Because of their addictive nature, medical professionals have done a lot in recent years to minimise the use of opioids, especially the length of time they are taken for following surgery. Patients receiving opioids for longer than a week post-surgery were found to double their risk of using these drugs for more than a year.

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