Making the right choice can be the difference between winning and losing, both in the National Football League and in the world of fantasy football. Case in point: In the 1998 NFL draft, Peyton Manning and Ryan Leaf were the two unquestioned top quarterbacks in the class. The Colts had a tough decision to make with the No. 1 pick, and they chose Manning. He went on to become a 14-time Pro Bowler, win two Super Bowls, multiple MVPs and was inducted into the Pro Football Hall of Fame.
The Colts chose wisely.
Imagine, on the other hand, if they had selected Leaf? He went on to play just three seasons, two with the team that drafted him, the Chargers. He had zero Pro Bowls, zero MVPs, zero Super Bowls and finished his career with a 4-17 record.