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The Hindu
The Hindu
Technology
Priyali Prakash

Explained | 2022 Nobel Prize winner Svante Pääbo’s research on human evolution

The story so far: The 2022 Nobel Prize for Physiology or Medicine has been awarded to Swedish geneticist Svante Pääbo for his research in the field of genomes of extinct hominins and human evolution.

“Thanks to Svante Pääbo’s discoveries, we now understand that archaic gene sequences from our extinct relatives influence the physiology of present-day humans. One such example is the Denisovan version of the gene EPAS1, which confers an advantage for survival at high altitude and is common among present-day Tibetans. Other examples are Neanderthal genes that affect our immune response to different types of infections,” the academy’s citation read.

Dr. Pääbo’s research has resulted in the rise of a new scientific disciple called paleogenomics, which is the study and analysis of genes of ancient or extinct organisms.

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