A review published in the journal Neuroprotection argues that exercise does more than improve strength, balance and mobility. It also stimulates the release of molecules known as "exerkines", which travel through the bloodstream and may reduce inflammation, protect nerve cells and support brain function. That raises new questions about whether health systems should place greater emphasis on physical activity as part of routine neurological care.
While researchers caution that much of the evidence remains preclinical, the findings point towards a growing understanding of how skeletal muscle communicates with the brain.