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LiveScience
LiveScience
Nicoletta Lanese

Estrogen in both the male and female brain shapes responses to trauma, study suggests

A colorful scan of a human brain, with various regions in red, green or white. .

High estrogen in the brain's memory center may worsen one's resilience against traumatic events, swaying the tendency to develop memory problems or post-traumatic stress in the aftermath, a new study in mice suggests.

The research, published in April in the journal Neuron, explored the effects of estrogen in the mouse brain. It zoomed in on the hippocampus, a key part of the brain involved in learning and memory. Both male and female mammals produce significant amounts of estrogen in the hippocampus, despite it often being framed as a "female" hormone.

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