Bristol's Harry Randall will start once more for England against Wales, in place of Ben Youngs, who could become England's all-time record appearance maker if he comes off the bench.
Eddie Jones has made four changes to his starting XV with Courtney Lawes coming in for Nick Isiekwe to captain the side from blindside flanker.
Manu Tuilagi also returns in place of Joe Marchant at inside-centre, with the Sale man making his first England appearance since the autumn internationals at inside-centre with Henry Slade and Marcus Smith either side of him.
