Elden Ring DLC: Miquella's Great Rune use and effect in Shadow of the Erdtree

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Players who manage to find and defeat the secret Scadutree Avatar boss in the Elden Ring: Shadow of the Erdtree DLC will notice that in addition to its Remembrance of the Shadow Sunflower, it also drops an item with quite a bit of significance: Miquella's Great Rune. You may recall that "Somewhere, a great rune has broken" message that popped up while exploring Scadu Altus; that rune was Miquella's, and you've just found what remains of it.