Tight bowling by the Netherlands restricted Pakistan to just 206 runs with captain Babar Azam top scoring with 91 in the third one-day international in Rotterdam on Sunday.
Pakistan won the toss and elected to bat on a cool and slightly overcast day, with another big score expected off the dry and bat-friendly pitch.
But Dutch paceman Vivian Kingma struck early when the first ball of his bowling spell saw the bails flying in the second over, sending opener Abdullah Shafique back to the clubhouse at the VOC cricket ground for two runs.