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Natalie C. Tronson, Associate Professor of Psychology, University of Michigan

Do hormonal contraceptives increase depression risk? A neuroscientist explains how they affect your mood, for better or worse

Hormonal contraceptives have functions that go beyond just birth control. Mindful Media/E+ via Getty Images

More than 85% of women – and more than 300 million people worldwide at any given time – use hormonal contraceptives for at least five years of their life. Although primarily taken for birth control, many people also use hormonal contraceptives to manage a variety of symptoms related to menstruation, from cramps and acne to mood swings.

For up to 10% of women, however, hormone contraceptives can increase their risk of depression. Hormones, including estrogen and progesterone, are crucial for brain health. So, how does modifying hormone levels with hormone contraceptives affect mental health?

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