Jordan Henderson returns to the Liverpool team as they look to go top of the Premier League at Manchester City.
Henderson was a second-half substitute in Tuesday night's 3-1 win at Benfica in the Champions League but is back in the midfield and captaining the side alongside Fabinho and Thiago Alcantara.
Diogo Jota also returns up top as he looks to add to his 20-goal haul already this season with Luis Diaz dropping to the bench for the Portugal international.
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As expected, Joel Matip comes back into the team in place of Ibrahima Konate with Trent Alexander-Arnold, Virgil van Dijk and Andy Robertson all keeping their place from the win in Lisbon this week.
Liverpool: Alisson; Alexander-Arnold, Matip, Van Dijk, Robertson; Fabinho, Thiago, Henderson; Salah, Jota, Mane.
Subs: Kellher, Konate, Milner, Keita, Firmino, Gomez, Jones, Tsimikas, Diaz.
Man City: Ederson; Walker, Stones, Laporte, Cancelo; Rodri, Silva, De Bruyne; Jesus, Foden, Sterling.
Subs: Steffen, Ake, Gundogan, Grealish, Zinchenko, Fernandinho, Mahrez, McAtee, Lavia.
