There's a well-known movie history between Wolverine and Deadpool, going all the way back to Deadpool's first ill-fated movie appearance in Wolverine's first ever solo film - even if that depiction of their pairing left fans (and even the actors) cold.
But with Deadpool and Wolverine bringing Hugh Jackman out of retirement to give the Best There Is and the Merc With a Mouth the duo adventure they deserve, we've got every hope in the world that Marvel Studios taps into the secret comic book history between Logan and Wade Wilson.
Wolverine and Deadpool's ties go way back in comics, primarily through the Weapon X program, as loosely adapted in the aforementioned film X-Men Origins: Wolverine - and there's much more to their relationship and even their Weapon X connections than you may realize.
The Weapon X Program
As we said, the biggest connection between Deadpool and Wolverine comes from the Weapon X program, an experimental program run by the Canadian and US governments to create super-soldiers and living weapons to act as spies, soldiers, and superheroes in the service of the governments that made them.
Both Wolverine and Deadpool were experimented on by Weapon X (which is itself part of a larger program called Weapon Plus that goes back as far as WWII and the transformation of Steve Rogers into a super-soldier).
Wolverine's involvement in Weapon X predates Deadpool's, with Weapon X being responsible for injecting Adamantium into Wolverine's bones, and for wiping and scrambling his mind, leading to the long-running mysteries about his true past and identity.
Oddly enough, as a later recruit to the Weapon X program, the experiments that turned Wade Wilson into Deadpool were partially based on Wolverine's mutant physiology, with Wolverine's own mutant healing factor providing the genetic basis for Deadpool's artificial healing factor.
That strange secret was revealed way back in Deadpool/Death Annual '98, an issue in which Deadpool teams up with Marvel's physical embodiment of Death (and which we named one of the best Deadpool stories of all time).
But rather than a retcon, the connection between Deadpool and Wolverine was envisioned from the start of his creation by artist Rob Liefeld, who has stated over the years that Deadpool's history with the Weapon X program was baked in all the way back when he made his first appearance in 1991's New Mutants #98. And indeed, those connections have been seeded throughout Deadpool's history.
Some of this history was on display in the not-very-well-received 2009 film X-Men Origins: Wolverine, in which Ryan Reynolds's fast-talking Wade Wilson is turned into a weird kind of living weapon with the powers of multiple mutants (infamously with his mouth sewn shut), including Wolverine's healing factor. Deadpool's initial film origin was essentially discarded for the first Deadpool movie (and meta-acknowledged for laughs in the sequel), though Wade was still given an artificial healing factor - something that may factor into Wolverine and Deadpool's movie team-up.
X-Force
Even though Deadpool isn't a mutant, he's often been associated with mutants and mutant teams due to his connections to the Weapon X program and to other concepts and characters in X-Men continuity. He's also been part of an X-Men team - the hardcore, killer black-ops team known as X-Force - which he served on alongside Wolverine.
Deadpool's connections to X-Force go back to his earliest introductions in the Marvel Universe in New Mutants, the title that became X-Force right after Deadpool's debut.
The original X-Force was a paramilitary team that broke away from the X-Men under the leadership of the enigmatic mutant Cable, who Deadpool also has a long history with. But the X-Force name was later revived as the X-Men team that takes on the most violent, brutal missions, often acting in secret from other mutants.
In the 2010 title Uncanny X-Force, Deadpool and Wolverine are two of the core characters of the squad alongside fellow Weapon Plus subject Fantomex, and several other mutants with a killer edge.
Deadpool and Wolverine's shared history with the Weapon Plus program plays a central role in several stories from the title, as does their shared willingness to do things that are at best morally questionable in pursuit of a noble goal.
Deadpool fans will remember a very different (and tragically less effective) version of X-Force in Deadpool 2. But unlike in the film, the team is alive and well in comics, with Wolverine appearing as a core member of the current X-Force title.
Weirdly enough, Deadpool and Wolverine have also both been Avengers - though not at the same time. Wolverine first joined Earth's Mightiest Heroes back in 2005 for the New Avengers relaunch following the original version of the team's dissolution in Avengers: Disassembled.
As for Deadpool, he joined up for the third incarnation of the title Uncanny Avengers in the wake of the 2015 Secret Wars event, which centered on a team of humans, mutants, Inhumans, and others from around the Marvel Universe all coming together as the 'Avengers Unity Squad.'
Wolverine and Deadpool in the MCU
The connection between Deadpool, Wolverine, and the Avengers - as well as Secret Wars - has some tantalizing potential implications for the MCU. But will they go there?
For now, we're primarily expecting that Deadpool 3 will focus on the biggest connection between Deadpool and Wolverine: Weapon X and their shared healing factor. Deadpool's healing factor has been a plot point since his first film, so there's a possible 'in' for that kind of story already on the table.
And moreover, even if Wolverine and Deadpool's shared healing factor isn't a plot point in Deadpool 3, the fact that they're both nigh-invincible badasses is undoubtedly going to be on display - especially since the film will be R-rated.
The secret history of Weapon X is a big part of some of the best Wolverine comics of all time.
