COVID‑19 vaccination during pregnancy has shown promise in reducing the risk of preeclampsia and improving overall pregnancy outcomes. Receiving a full vaccine series plus boosters can help lower maternal inflammation, support vascular health, and reduce the chances of preterm birth and perinatal complications.
According to a study conducted by the INTERCOVID Consortium analyzing 6,527 pregnant individuals across 18 countries, vaccinated individuals experienced a 33% reduction in preeclampsia odds, independent of SARS-CoV-2 infection. High-risk groups, such as those with diabetes or hypertension, had even stronger benefits, with reductions up to 42%. These results suggest that maternal vaccination may modulate immune and vascular pathways involved in preeclampsia, offering protection beyond COVID‑19 prevention.
