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LiveScience
LiveScience
Simon Spichak

Could vaccines prevent and treat Alzheimer's disease?

a female medical provider wearing a short white lab coat and name tag prepares to give an older male patient a vaccine in his arm. He's waring a yellow polo and looking away from the camera towards the medical provider

Despite decades of Alzheimer's research, scientists have not found a treatment that halts or dramatically slows the disease. Now, scientists are investigating if a completely new approach — so-called Alzheimer's vaccines — could alter the disease's course.

The logic behind this effort? Much of the previous research has placed beta-amyloid plaques, clumps of protein that accumulate in the brains of Alzheimer's patients, front-and-center. But drugs that remove beta-amyloid plaques alone don't seem to have much impact on the disease course. So some researchers have proposed that the plaques are a consequence, rather than a cause of Alzheimer's.

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