Nuno Tavares starts at left back for Arsenal in their crucial Premier League match against Southampton on Saturday afternoon.
The Portuguese defender has found himself sidelined from the team since a difficult performance against Crystal Palace, but returns to the line-up for the game at St Mary's.
Sambi Lokonga starts alongside Granit Xhaka in midfield, while Martin Odegaard and Bukayo Saka support Gabriel Martinelli and Eddie Nketiah upfront.
Gunners boss Mikel Arteta has called up a number of youngsters to the first team squad including Zak Swanson, Miguel Azeez, Omari Hutchinson and Mazeed Ogungbo.
All four academy products have been training regularly with the senior squad in recent weeks as Arteta looks to find a solution to the injuries to Thomas Partey and Kieran Tierney.
Arsenal XI: Ramsdale, Cedric, White, Gabriel, Tavares, Xhaka, Lokonga, Odegaard, Saka, Martinelli, Nketiah.
Subs: Leno, Holding, Ogungbo, Swanson, Elneny, Azeez, Smith Rowe, Hutchinson, Pepe.