Rob Holding starts in defence against Burnley as Mikel Arteta makes one change from the team that lost to Liverpool on Thursday.
The Gunners are without Takehiro Tomiyasu who started the game against the Reds despite not being fully fit.
Martin Odegaard and Sambi Lokonga start in midfield, while Emile Smith Rowe and Gabriel Martinelli support Alexandre Lacazette upfront.