Rob Holding starts in defence against Burnley as Mikel Arteta makes one change from the team that lost to Liverpool on Thursday.
The Gunners are without Takehiro Tomiyasu who started the game against the Reds despite not being fully fit.
Martin Odegaard and Sambi Lokonga start in midfield, while Emile Smith Rowe and Gabriel Martinelli support Alexandre Lacazette upfront.
Bernd Leno returns to the substitutes bench following a back injury, with the German shot stopper expected to leave the club in the final days of the transfer window.
Salah-Edinne, Omari Hutchinson, Charlie Patino, Ryan Alebiousu and Mika Biereth make up a young array of substitutes for Gunners boss Mikel Arteta to choose from.
Arsenal XI: Ramsdale, Holding, White, Gabriel, Tierney, Odegaard, Lokonga, Smith Rowe, Saka, Martinelli, Lacazette (c).
Subs: Leno, Tavares, Chambers, Alebiousu, Salah-Edinne, Hutchinson, Patino, Nketiah, Biereth.
