For anyone who relies on coffee to start their day, coffee wilt disease may be the most important disease you’ve never heard of. This fungal disease has repeatedly reshaped the global coffee supply over the past century, with consequences that reach from African farms to cafe counters worldwide.
Infection with the fungus Fusarium xylarioides results in a characteristic “wilt” in coffee plants by blocking and reducing the plant’s ability to transport water. This blockage eventually kills the plant.
Some of the most destructive plant pathogens in the world infect their hosts in this way. Since the 1990s, outbreaks of coffee wilt have cost over US$1 billion, forced countless farms to close and caused dramatic drops in national coffee production. In Uganda, one of Africa’s largest producers, coffee production did not recover to pre-outbreak levels until 2020, decades after coffee wilt was first detected there. And in 2023, researchers found evidence that coffee wilt disease had resurfaced across all coffee-producing regions of Ivory Coast.
