A two-year randomized trial across 11 Latin American countries found that older adults at risk of dementia gained more cognitive benefit from a structured, coach-led lifestyle program than from a flexible self-guided version of the same approach.
Both groups improved. The difference was in magnitude. Participants in the structured arm showed roughly 55% greater improvement in global cognitive function than those in the flexible arm, according to results presented at the Alzheimer's Association International Conference in London on July 13 and published simultaneously in The Lancet. Episodic memory showed the largest single effect.
