Washington [US]: A new technique analyzing urine extracellular vesicles (uEVs) -- cell-derived nanoscale spherical structures involved in multiple biological functions -- in urine samples identifies changes in the kidneys earlier than conventional methods and can also predict renal function decline.
A team at the University of Tokyo studied eurine samples from children with and without chronic kidney disease CKD. They found that the size and content of uEVs change with decreasing kidney function. This proof of concept could help with developing new urine tests that can catch the disease earlier, as well as the development of similar tests for other diseases.
