Levi Colwill starts for Chelsea against Brighton tonight.
Reece James, however, will not be involved.
The 23-year-old is unlikely to start after doing his first training session on Friday after a period out with illness.
Mauricio Pochettino had also explained that, despite playing Premier League opposition in the Summer Series, he will continue to use his young players on Saturday night.
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Trevoh Chalobah felt his Achilles in the last match and does not play but Kepa Arrizabalaga and Thiago Silva are be handed their first involvements.
Chelsea will also play with a young midfield again after Andrey Santos, Carney Chukwuemeka and Conor Gallagher involved.
Pochettino also starts Christopher Nkunku and Raheem Sterling up front together for the first time.
Starting Chelsea XI: : Kepa, Gusto, Silva, Colwill, Chilwell, Santos, Gallagher, Sterling, Chukwuemeka, Maatsen, Nkunku .
Injured: None
Doubt: Chalobah
Time and date: 12am BST on Sunday, July 23, 2023
Location: Lincoln Financial Field, Philadelphia